Age well and live longer.
Ageing, is an increasingly interesting subject to me. One of my biggest fears, and I am sure one of your’s too, is growing old and suffering from the plethora of conditions we can all see affecting the older generations today.
For the people who are currently in their 80's and 90's, the knowledge we have today about how to attenuate the aging process through training, lifestyle and nutrition, is of little help. The awesome power of strength training, movement practice, correct diet and targeted supplementation is most potent when applied early in the degenerative process. One such very powerful nutrient is Resveratrol. An antioxidant found in grapes that has a significnat impact on a cellular level that can positively impact againg and help protect against some of todays biggest killers.
Resveratrol can have the following benefits when taken daily:
Slower ageing at the cellular level
Protection from neurodegenerative diseases like Parkinson’s and Alzheimers
Protection from diabetes
Protection from heart disease
Protection from cancer
Protection from obesity
Pretty impressive. To some of you, it may sound a bit too good to be true. Well, I thought so too, which is why I did my research and read over 120 scientific papers on the nutrient, 60 of which have been included in the references. When I started looking into the science behind resveratrol I honestly could not believe how much there was, how much it did or how legitimate a strategy it is to include this nutrient in your supplement plan.
At a dose of 250mg < 500mg, you can reap all the benefits of this powerful antioxidant. I have started taking it daily and will probably continue to do so for as long as I can buy it.
At this point, some of you may trust me enough to go straight ahead and order, maybe you don't have time to read the rest of the article, which I appreciate is a little lengthy.
For those of you who have as much of a thirst for information as I do, I have done my best to distill the research into the rest of this article.
I highly recommend reading the rest of this article to truly understand what you might be missing out on not knowing about RSV. I will release an audio peice on the subject soon for those who do not have time to read the full thing. If you’re the type of person who needs robust proof. Please feel free to check out my references.
All About Resveratrol.
Amazing benefits, it all starts in the mitochondria. For those who don’t know, the mitochondria are tiny organelles. They are microscopic machinery within all human cells. They are as old as life itself and are essentially what provides us with energy. There can be thousand within a cell without them we cannot respire aerobically. These guys literally power our bodies. This understanding is crucial to understanding how one nutrient can have such a fantastic impact on our health.
When I first heard that resveratrol could impact such a wide array of things I was very sceptical, as I am sure many of you are. It made perfect sense when I learnt how it impacts the mitochondria. As an extension of better mitochondrial health, you get better cell health, which translates into better organ health and better organism health.
One of the pathways through which this impact is achieved is through protecting the mitochondria from themselves. When mitochondria burn glucose for energy they produce reactive oxygen species or ROS for short. These ROS oxidise the cell from the inside out. What is oxidation? when you cut an apple inhale and leave it for a few minutes you see the flesh go brown. That is oxidation. When you leave metal unprotected from water and oxygen you get rust, which is oxidation. Oxidation is, in essence, a slow process of decay. Not something you want to have going on in your cells to any great extent. RSV protects mitochondria against these ROS as well as preventing as much generation of the ROS in the first place.
Another way in which the mitochondria protect against oxidation is by improving fatty acid oxidation within the mitochondria. When mitochondria burn fatty acids instead of glucose less advanced glycation end products are produced, less ROS are produced and the mitochondria are, as a result, less damaged. This is also one of the mechanisms that RSV can protect against diabetes, by preserving the mitochondria’s ability to burn fat for fuel. Incidentally, this is also one of the reasons why a fat based diet is superior to a carb based diet, less oxidation of the cells.
This process is especially evident in the brain, where RSV protects against neurodegenerative diseases through this exact pathway. effectively preventing and cleaning up the ROS produced by glucose metabolism in the brain.
mitochondria are absolutely critical to our health. As such having the ability to preserve their numbers is a good thing that will help keep us alive and well. certain types of exercise, especially hypertrophy training coupled with aerobic activity like hiking, is very good at maintaining higher numbers of healthy mitochondria. RSV, too, stimulates mitochondrial biogenesis (the production of new mitochondria). This is another way in which RSV helps protect against ageing and promotes better energy levels. Its effect is so pronounced RSV is being used as a therapy for various forms of chronic fatigue syndrome.
Autophagy is a biological process gaining a lot of attention recently. It turns out that when we fast for a significant period of time, our bodies turn on a process called autophagy. This process involves breaking down used, dead tissues, cells and organelles like dead mitochondria and recycling them for use somewhere else. As it turns out, this process is very good for life extension. This is one of the main reasons for the intermittent fasting community speaking about the longevity benefits of fasting.
RSV turns off the very same pathway (SIRT-1) that fasting does. RSV stimulates autophagy without fasting being necessary. That contributes to longevity and is reportedly anti-carcinogenic.
Apoptosis is a medical term also referred to as programmed cell death. It is a process where a cell essentially self-terminates. It can be a good thing or a bad thing depending on the cell. When it's a cancer cell its a good thing and when it's a brain cell its a bad thing (very simply). RSV causes apoptosis is cancer cells but not healthy cells. It is so good at this that it is being proposed, and in some cases used as a chemopreventive measure in early detection cancer patient with some forms of cancer.
RSV’s impact on apoptosis has caused it to be recommended as a cancer preventative dietary supplement.
RSV also helps chemotherapy target the cancer cells with greater accuracy, leading to less collateral damage of healthy cells. When coupled with the impact of RSV on mitochondria, it starts to look like a very appealing adjunct to chemotherapy. With the only downside being loose bowls at a dose of 5g. Which probably won't be a problem as the maximum benefits seem to be gained at only 500mg.
Other cancer prevention pathways.
The impact of RSV on mitochondria can also be assigned a degree of cancer prevention benefit. Cancer cells need an acidic, low oxygen environment to thrive and multiply, they also thrive on sugar, but cannot metabolise fats. By preserving the mitochondrial capacity to burn fats and preventing oxidation, ROS and a reliance on glucose, it is argued that an anti-cancer effect is achieved.
The heart tissue is among the most heavily concentrated in mitochondria out of every tissue in the body. Which makes sense when you think that the heart is respiring aerobically non-stop our whole lives. By stimulating biogenesis, preventing ROS production and protecting against oxidation, it’s no surprise that RSV has show cardioprotective effects in multiple studies.
Taking RSV literally has no downsides, it’s not extremely expensive, the benefits are legitimate and wide-ranging and the dose needed to experience such benefits is quite low. As with all supplements, you get what you pay for. I personally take the Poliquin brand because I trust their potency. They use only trans-resveratrol, which is the active form most often used in the actual research. They do not use inferior forms that have not been tested and they guarantee the potency and purity of everything they do. If you are an athlete you can take this with confidence that you are safe from dropping tests etc.
I personally will take RSV every day for the rest of my life.
Thank you for taking the time to read to the end of this letter. It means a lot that I can help people through my pursuits to help myself and my family.
I hope I have Inspired you to take action and order yourself some resveratrol now. If you are an EP client we will be offering an Autodrop service for this product every two months or every month. So make sure to click the right link below if you want the long term option.